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Try out PMC Labs and tell us what you think. Learn More. We describe enrollment for the One Thousand Strong panel, present characteristics of the panel relative to other large U. Milestone 1 was screening eligible and providing informed consent. Milestone 2 involved completing an hour-long at-home computer-assisted self-interview CASI survey.

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Compared to those who completed milestones: those not passing milestone 1 were more likely to be non-White and older; those not passing milestone 2 were less likely to have insurance or a primary care physician; and those not passing milestone 3 were less educated, more likely to be bisexual as opposed to gay, more likely to live in the Midwest, had fewer male partners in the past year, and less likely to have tested for HIV in the past year.

Effect sizes for ificant findings were small. This indicates high feasibility and acceptability of incorporating self-administered biological assays into otherwise fully online studies.

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Differences in completion of study milestones indicate a need for further investigation into the reasons for lower engagement by certain groups. Moreover, much of what we know about GBM has been based on samples where HIV has taken its greatest toll—those in urban epicenters and who report HIV sexual risk behaviors.

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As a result, less is known about U. GBM who live outside of urban centers and those who do not report recent sexual risk. Using keyword searches of common terms e. In short, researchers have responded to the expansion of Internet use among GBM by adopting the Internet as a tool to study them Chiasson et al.

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This has afforded researchers the opportunity to identify and study GBM who may not live in urban centers or are otherwise geographically diverse Chiasson et al. For online recruitment, a of researchers have enrolled geographically, racially, and ethnically diverse samples of GBM from across the U.

Others have enrolled diverse samples across the U. In so doing, researchers have advertised on websites via banner or pop-upor partnered with website owners such that websites directly contacted their membership inviting them to participate in a study.

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The benefit of recruiting via hook-up websites and apps—particularly for HIV prevention and research—is that GBM can be engaged in research and interventions in the exact environments in which they are concurrently negotiating sexual encounters with potential partners Grov, Breslow, et al. These samples, however, are skewed toward men who are more sexually active and thus potentially riskier than GBM more generally Parsons et al. That is that recruiting men from sex sites may not benefit researchers seeking a more general gay sample with varied, and especially lower, sexual risk.

Additionally, for many exclusively online approaches to data collection—regardless of whether social or sexual networking websites were used—there is the opportunity for invalid submissions e. Other researchers have used a combination of both face-to-face e.

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We know of only one study in which a sample of GBM participants were recruited first via random digit dialing—thus purporting U. In this study, those who did not have a computer or access to the Internet were provided with both as necessary. The larger panel consisted of over 40, households, of which were gay men and bisexual men.

In summary, it is becoming increasingly essential to study U. To overcome some of the aforementioned limitations, one approach to recruiting GBM for online assessment could be partnering with Internet marketing and polling entities in search of more representative samples of GBM from across the U. Chang, This involves partnering with a consumer marketing research firm to recruit potential participants through their existing panel of respondents, while also ensuring that such panelists are representative of GBM more broadly Voytek et al.

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However, research utilizing this approach has been limited for online research with GBM. Researchers have established the feasibility and acceptability of enrolling and engaging large U. Building upon this work, researchers have begun exploring ways to additionally engage GBM in at-home HIV testing, with much promise of feasibility and acceptability in spite of fairly limited data Khosropour et al.

Khosropour et al. Participants completed both online surveys and returned an at-home HIV test kit finger stick, dried blood spot.

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Sharma et al. For GBM, high acceptability and feasibility for self-sampling of rectal specimens for STI screening was found in a study conducted by Wayal et al. A majority of men were willing to self-sample at home, providing further support for at-home testing. Meanwhile, less is known about the feasibility and acceptability of completing at-home self-administered urethral and rectal STI screening. In addition to the present study, at-home self-administered testing is currently being used in ongoing NIH-funded studies and thus data on feasibility and acceptability are forthcoming.

Meanwhile, comparable research with presumably mostly heterosexual women and men has noted mixed with the feasibility and acceptability of at-home STI testing.

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One study indicated strong acceptability for vaginal swabs to test for bacterial STIs Gaydos et al. In their study, Gaydos et al.

Another study of adults in Sweden reported on online advertising for an at home urine collection kit to test for chlamydia. The website received 19, visits which resulted in test requests among women For the present study, we present characteristics of the One Thousand Strong panel, an ongoing longitudinal study of GBM from across the U.

We compared the One Thousand Strong panel to samples from other U. The One Thousand Strong panel is a longitudinal study prospectively following a U. Analyses for the present manuscript are based on our recruitment and enrollment data. Although a non-probability panel in-and-of itself, CMI is able to target individuals based on predetermined characteristics and invite them to participate in research studies.

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In so doing, we used data from the U. Census with regard to the distribution of same-sex households and racial ethnic composition by state to populate our recruitment parameters. That is, states with more same-sex households e.

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Census Bureau, Through our partnership, CMI identified participants and briefly screen them for eligibility. Those deemed preliminarily eligible had their responses and contact information shared with the research team, and we then independently contacted and followed participants for full enrollment and longitudinal assessment.

To be preliminarily eligible for One Thousand Strongparticipants had to reside in the U. Box, and report residential stability i.

We excluded heterosexually identified MSM because the HIV prevention needs as well as interventions targeting these individuals would be vastly different from those targeting gay and bisexually identified men. Participants were required to be sexually active in the past year; however, please note that we did not require men to report HIV risk behavior i. Men needed a digital camera in order to take a picture of their at-home HIV test and send them to us so could be verified. We excluded those with only a P. Box because testing kits may not have been delivered, and we excluded those having moved more than twice in the past months e.

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We staggered enrollment over a period of 6 months April —October such to maintain sufficient staffing resources to guide participants through the enrollment process e. Participants had to pass three milestones in order to be considered fully enrolled in the One Thousand Strong panel and each milestone involved multiple steps.

All invited participants were over the age of 18, male, gay or bisexually identified, and had access to the Internet, and were specifically targeted with regard to location, age range, race, and ethnicity in order to reach out to a sample that was reflective of U. Census characteristics.

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s were tracked as opened, screener started, or bounced. Participants were told they would have to complete a brief 2 minute online screener to determine if they met preliminary eligibility criteria ly described.

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Following the screening survey, the One Thousand Strong study was described in its entirety along with an introduction video explaining the study objectives. Consent for CMI to share participant contact information with the research team was obtained. Preliminarily eligible participants who provided consent had their contact information shared with the research team and we then independently contacted participants to continue the enrollment procedures.

Preliminarily eligible participants who completed Milestone 1 were sent an by the research team to complete an at-home baseline CASI survey via Qualtrics survey software qualtrics. The baseline CASI survey included a link to a welcome video that introduced the research staff and explained the survey procedures. The survey itself included questions on a range of topics including depression, substance use, HIV testing history, tobacco use, gay community attachment, and sexual behavior.

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In the event they closed their browser window, the survey would where they left off when the link was clicked again. Of those who completed the baseline CASI, the median time to survey completion was 78 minutes, which includes any breaks taken by participants.

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We timed kit arrival to coincide with an to participants. This contained a link for participants to watch an instructional video on how to proceed with the testing kit as well as a brief 5 minute survey to complete following testing procedures.

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Those who tested positive for an STI were phoned to facilitate connecting them to treatment with a healthcare provider. Those who tested negative for STIs received an with their .

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Preliminarily eligible participants were considered fully enrolled in the panel when they completed all components of the enrollment process and their HIV test were negative. Project staff members were available to assist participants in all phases of the enrollment process and, as necessary, we reached out to participants up to two reminders, two text messages, and four phone calls over a one month period to encourage timely completion of enrollment steps.

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Measures used in this manuscript included variables collected at different points during the enrollment process e. These include demographic characteristics, alcohol and drug use and sexual behavior. During the CMI screening, participants reported of male sex partners in the past 12 months. During the baseline CASI, participants were asked whether they currently had primary and casual sexual partners in the past 3 months and of condomless anal sexual acts CAS with their partners.

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Sexual risk was determined as having CAS with any casual male partner or a male main partner whose status was HIV-positive or unknown. First we describe univariate characteristics of the One Thousand Strong panel relative to other large scale and U. Other studies included for comparative purposes were selected based on their being large-scale U.

Ten studies met our inclusion criteria.

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Although not a sample from across the U. Where appropriate, we used chi-square and t -tests to compare our data to those of others. Next, we compared demographic characteristics of those who responded to the CMI invitation versus those who did not. We then compared participants who completed various enrollment milestones with those who did not.

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